Cart
sales@molnova.com
Home - Products - Apoptosis - Apoptosis - NSC 745887

NSC 745887

CAS No. 54490-26-5

NSC 745887( NSC745887 )

Catalog No. M14957 CAS No. 54490-26-5

NSC 745887 is a small molecule that effectively inhibits the proliferation of various cancers by trapping DNA-topoisomerase cleavage.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 873 Get Quote
50MG 1782 Get Quote
100MG 2250 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    NSC 745887
  • Note
    Research use only, not for human use.
  • Brief Description
    NSC 745887 is a small molecule that effectively inhibits the proliferation of various cancers by trapping DNA-topoisomerase cleavage.
  • Description
    NSC 745887 is a small molecule that effectively inhibits the proliferation of various cancers by trapping DNA-topoisomerase cleavage, shows anticancer effects against human GBM cells via suppressing DcR3-associated signaling pathways; increases the sub-G1 population in dose- and time-dependent manners in GBM cells, increases expression of γH2AX and causes DNA fragmentation leading to DNA damage; suppresses the [18F]-FDG-specific uptake value in brain tumors.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC745887
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    54490-26-5
  • Formula Weight
    260.252
  • Molecular Formula
    C16H8N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(C1=CC=C2N=CC=NC2=C1C3=O)C4=C3C=CC=C4
  • Chemical Name
    Naphtho[2,3-f]quinoxaline-7,12-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fann LY, et al. Oncotarget. 2017 Dec 27;9(15):11922-11937.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Polygalacin D

    Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities.

  • Methyl pyropheophorb...

    Methyl pyropheophorbide-a (MPPa) is a chlorine photosensitizer and a derivative of chlorophyll a. It is photodynamically active, induces apoptosis and inhibits tumor growth, and can be used in photodynamic therapy (PDT) of cancer.

  • Sodium Oxamate

    Sodium Oxamate is an LDH inhibitor.?Sodium oxamate (SO) induces G2/M cell cycle arrest via downregulation of the CDK1/cyclin B1 pathway and promotes apoptosis through enhancement of mitochondrial ROS generation.

Sign In Join Free